Inflammatory Macrophages Induce Nrf2 Transcription Factor-dependent Proteasome Activity in Colonic NCM460 Cells and Thereby Confer Anti-apoptotic Protection

Adaptation of epithelial cells to persistent oxidative stress plays an important role in inflammation-associated carcinogenesis. This adaptation process involves activation of Nrf2 (nuclear factor-E2-related factor-2), which has been recently shown to contribute to carcinogenesis through the inducti...

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Главные авторы: Sebens, Susanne, Bauer, Iris, Geismann, Claudia, Grage-Griebenow, Evelin, Ehlers, Stefan, Kruse, Marie-Luise, Arlt, Alexander, Schäfer, Heiner
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2011
Предметы:
Molecular Bases of Disease
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220482/
https://ncbi.nlm.nih.gov/pubmed/21990354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.274902
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