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The fatal alliance of cancer and T cells: How pancreatic tumor cells gather immunosuppressive T cells
Immune evasion is a hallmark of cancer. We recently identified the adhesion molecule L1CAM as biomarker of pancreatic ductal adenocarcinoma (PDAC) associated with poor prognosis. During inflammation-associated carcinogenesis, L1CAM drives the enrichment of highly immunosuppressive CD4(+)CD25(-)CD69(...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4126073/ https://ncbi.nlm.nih.gov/pubmed/25114835 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.29382 |
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