L1CAM promotes enrichment of immunosuppressive T cells in human pancreatic cancer correlating with malignant progression

Regulatory T cell (T‐reg) enrichment in the tumor microenvironment is regarded as an important mechanism of tumor immune escape. Hence, the presence of T‐regs in highly malignant pancreatic ductal adenocarcinoma (PDAC) is correlated with short survival. Likewise, the adhesion molecule L1CAM is upreg...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Mol Oncol
Asıl Yazarlar: Grage-Griebenow, Evelin, Jerg, Elfi, Gorys, Artur, Wicklein, Daniel, Wesch, Daniela, Freitag-Wolf, Sandra, Goebel, Lisa, Vogel, Ilka, Becker, Thomas, Ebsen, Michael, Röcken, Christoph, Altevogt, Peter, Schumacher, Udo, Schäfer, Heiner, Sebens, Susanne
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2014
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528528/
https://ncbi.nlm.nih.gov/pubmed/24746181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.03.001
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