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Cytoprotection “gone astray”: Nrf2 and its role in cancer

Nrf2 has gained great attention with respect to its pivotal role in cell and tissue protection. Primarily defending cells against metabolic, xenobiotic and oxidative stress, Nrf2 is essential for maintaining tissue integrity. Owing to these functions, Nrf2 is regarded as a promising drug target in t...

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Hlavní autoři: Geismann, Claudia, Arlt, Alexander, Sebens, Susanne, Schäfer, Heiner
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155833/
https://ncbi.nlm.nih.gov/pubmed/25210464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S36624
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