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Cytoprotection “gone astray”: Nrf2 and its role in cancer

Nrf2 has gained great attention with respect to its pivotal role in cell and tissue protection. Primarily defending cells against metabolic, xenobiotic and oxidative stress, Nrf2 is essential for maintaining tissue integrity. Owing to these functions, Nrf2 is regarded as a promising drug target in t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Geismann, Claudia, Arlt, Alexander, Sebens, Susanne, Schäfer, Heiner
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155833/
https://ncbi.nlm.nih.gov/pubmed/25210464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S36624
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