Nucleotides Acting at P2Y Receptors: Connecting Structure and Function

Eight G protein–coupled P2Y receptor (P2YR) subtypes are important physiologic mediators. The human P2YRs are fully activated by ATP (P2Y(2) and P2Y(11)), ADP (P2Y(1), P2Y(12), and P2Y(13)), UTP (P2Y(2) and P2Y(4)), UDP (P2Y(6) and P2Y(14)), and UDP glucose (P2Y(14)). Their structural elucidation is...

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Détails bibliographiques
Publié dans:Mol Pharmacol
Auteurs principaux: Jacobson, Kenneth A., Paoletta, Silvia, Katritch, Vsevolod, Wu, Beili, Gao, Zhan-Guo, Zhao, Qiang, Stevens, Raymond C., Kiselev, Evgeny
Format: Artigo
Langue:Inglês
Publié: The American Society for Pharmacology and Experimental Therapeutics 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4518082/
https://ncbi.nlm.nih.gov/pubmed/25837834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.114.095711
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