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Nucleotides Acting at P2Y Receptors: Connecting Structure and Function

Eight G protein–coupled P2Y receptor (P2YR) subtypes are important physiologic mediators. The human P2YRs are fully activated by ATP (P2Y(2) and P2Y(11)), ADP (P2Y(1), P2Y(12), and P2Y(13)), UTP (P2Y(2) and P2Y(4)), UDP (P2Y(6) and P2Y(14)), and UDP glucose (P2Y(14)). Their structural elucidation is...

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Detalhes bibliográficos
Publicado no:Mol Pharmacol
Main Authors: Jacobson, Kenneth A., Paoletta, Silvia, Katritch, Vsevolod, Wu, Beili, Gao, Zhan-Guo, Zhao, Qiang, Stevens, Raymond C., Kiselev, Evgeny
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4518082/
https://ncbi.nlm.nih.gov/pubmed/25837834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.114.095711
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