Structure of the human P2Y(12) receptor in complex with an antithrombotic drug

P2Y receptors (P2YRs), a family of purinergic G-protein-coupled receptors (GPCRs), are activated by extracellular nucleotides. There are a total of eight distinct functional P2YRs expressed in human, which are subdivided into P2Y(1)-like receptors and P2Y(12)-like receptors(1). Their ligands are gen...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Zhang, Kaihua, Zhang, Jin, Gao, Zhan-Guo, Zhang, Dandan, Zhu, Lan, Han, Gye Won, Moss, Steven M., Paoletta, Silvia, Kiselev, Evgeny, Lu, Weizhen, Fenalti, Gustavo, Zhang, Wenru, Müller, Christa E., Yang, Huaiyu, Jiang, Hualiang, Cherezov, Vadim, Katritch, Vsevolod, Jacobson, Kenneth A., Stevens, Raymond C., Wu, Beili, Zhao, Qiang
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2014
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4174307/
https://ncbi.nlm.nih.gov/pubmed/24670650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13083
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