CHMP5 controls bone turnover rates by dampening NF-κB activity in osteoclasts

Physiological bone remodeling requires that bone formation by osteoblasts be tightly coupled to bone resorption by osteoclasts. However, relatively little is understood about how this coupling is regulated. Here, we demonstrate that modulation of NF-κB signaling in osteoclasts via a novel activity o...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Exp Med
Egile Nagusiak: Greenblatt, Matthew B., Park, Kwang Hwan, Oh, Hwanhee, Kim, Jung-Min, Shin, Dong Yeon, Lee, Jae Myun, Lee, Jin Woo, Singh, Anju, Lee, Ki-young, Hu, Dorothy, Xiao, Changchun, Charles, Julia F., Penninger, Josef M., Lotinun, Sutada, Baron, Roland, Ghosh, Sankar, Shim, Jae-Hyuck
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Rockefeller University Press 2015
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516796/
https://ncbi.nlm.nih.gov/pubmed/26195726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20150407
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