Zinc inhibits osteoclast differentiation by suppression of Ca(2+)-Calcineurin-NFATc1 signaling pathway

BACKGROUND: Zinc, an essential trace element, inhibits osteoclast differentiation in vitro and in vivo. The molecular mechanism for the inhibitory effect of zinc, however, is poorly understood. The purpose of this study was to investigate the effect of zinc and determine its molecular mechanism on r...

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Bibliografiske detaljer
Main Authors: Park, Kwang Hwan, Park, Boryung, Yoon, Dong Suk, Kwon, Seung-Hyun, Shin, Dong Min, Lee, Jin Woo, Lee, Hyun Gyu, Shim, Jae-Hyuck, Park, Jeon Han, Lee, Jae Myun
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3851046/
https://ncbi.nlm.nih.gov/pubmed/24088289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-11-74
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