Targeting of cancer stem cell marker EpCAM by bispecific antibody EpCAMxCD3 inhibits pancreatic carcinoma

Patients with pancreatic cancer have a poor survival rate, and new therapeutic strategies are needed. Epithelial cell adhesion molecule (EpCAM), suggested as a marker for cancer stem cells, is over-expressed on most pancreatic tumour cells but not on normal cells and may be an ideal therapeutic targ...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:J Cell Mol Med
Main Authors: Salnikov, Alexei V, Groth, Ariane, Apel, Anja, Kallifatidis, Georgios, Beckermann, Benjamin M, Khamidjanov, Akmal, Ryschich, Eduard, Büchler, Markus W, Herr, Ingrid, Moldenhauer, Gerhard
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley & Sons, Ltd 2009
Assuntos:
Molecular Oncology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4516549/
https://ncbi.nlm.nih.gov/pubmed/20196789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2009.00723.x
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares