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The detection of EpCAM(+) and EpCAM(–) circulating tumor cells

EpCAM expressing circulating tumor cells, detected by CellSearch, are predictive of short survival in several cancers and may serve as a liquid biopsy to guide therapy. Here we investigate the presence of EpCAM(+) CTC detected by CellSearch and EpCAM(–) CTC discarded by CellSearch, after EpCAM based...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Wit, Sanne de, Dalum, Guus van, Lenferink, Aufried T. M., Tibbe, Arjan G. J., Hiltermann, T. Jeroen N., Groen, Harry J. M., van Rijn, Cees J. M., Terstappen, Leon W. M. M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505332/
https://ncbi.nlm.nih.gov/pubmed/26184843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12270
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