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Expression of EpCAM(MF) and EpCAM(MT) variants in human carcinomas

AIMS: Regulated intramembrane proteolysis has been shown to be an important mechanism for oncogenic activation of epithelial cell adhesion molecule (EpCAM) through nuclear translocation of the intracellular domain EpICD. Recent studies have identified new membrane-bound EpCAM variants. To evaluate t...

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Bibliographic Details
Main Authors: Fong, Dominic, Seeber, Andreas, Terracciano, Luigi, Kasal, Armin, Mazzoleni, Guido, Lehne, Florian, Gastl, Guenther, Spizzo, Gilbert
Format: Artigo
Language:Inglês
Published: BMJ Publishing Group 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3995261/
https://ncbi.nlm.nih.gov/pubmed/24465008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jclinpath-2013-201932
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