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The detection of EpCAM(+) and EpCAM(–) circulating tumor cells

EpCAM expressing circulating tumor cells, detected by CellSearch, are predictive of short survival in several cancers and may serve as a liquid biopsy to guide therapy. Here we investigate the presence of EpCAM(+) CTC detected by CellSearch and EpCAM(–) CTC discarded by CellSearch, after EpCAM based...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Wit, Sanne de, Dalum, Guus van, Lenferink, Aufried T. M., Tibbe, Arjan G. J., Hiltermann, T. Jeroen N., Groen, Harry J. M., van Rijn, Cees J. M., Terstappen, Leon W. M. M.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505332/
https://ncbi.nlm.nih.gov/pubmed/26184843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12270
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