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A bispecific EpCAM/CD133 targeted toxin is effective against carcinoma

The discovery of chemoresistant cancer stem cells (CSCs) in carcinomas has created the need for therapies that specifically target these subpopulations of cells. Here we characterized a bispecific targeted toxin that is composed of two antibody fragments and a catalytic protein toxin allowing it to...

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Hlavní autoři: Waldron, Nate N., Barsky, Sanford H., Vallera, Daniel A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3994189/
https://ncbi.nlm.nih.gov/pubmed/23900680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11523-013-0290-9
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