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Amyloid Precursor-like Protein 2 and Sortilin Do Not Regulate the PCSK9 Convertase-mediated Low Density Lipoprotein Receptor Degradation but Interact with Each Other
Amyloid precursor-like protein 2 (APLP2) and sortilin were reported to individually bind the proprotein convertase subtilisin/kexin type 9 (PCSK9) and regulate its activity on the low-density lipoprotein receptor (LDLR). The data presented herein demonstrate that mRNA knockdowns of APLP2, sortilin,...
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發表在: | J Biol Chem |
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Main Authors: | , , , , , , , , , , , , , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
American Society for Biochemistry and Molecular Biology
2015
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4513119/ https://ncbi.nlm.nih.gov/pubmed/26085104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.647180 |
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