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Deletion of the Gene Encoding Proprotein Convertase 5/6 Causes Early Embryonic Lethality in the Mouse

PC5 belongs to the proprotein convertase family and activates precursor proteins by cleavage at basic sites during their transit through the secretory pathway and/or at the cell surface. These precursors include prohormones, proreceptors, growth factors, adhesion molecules, and viral glycoproteins....

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Detalhes bibliográficos
Main Authors: Essalmani, Rachid, Hamelin, Josée, Marcinkiewicz, Jadwiga, Chamberland, Ann, Mbikay, Majambu, Chrétien, Michel, Seidah, Nabil G., Prat, Annik
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1317638/
https://ncbi.nlm.nih.gov/pubmed/16354705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.1.354-361.2006
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