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The Multifaceted Proprotein Convertases: Their Unique, Redundant, Complementary, and Opposite Functions

The secretory proprotein convertase (PC) family comprises nine members: PC1/3, PC2, furin, PC4, PC5/6, PACE4, PC7, SKI-1/S1P, and PCSK9. The first seven PCs cleave their substrates at single or paired basic residues, and SKI-1/S1P cleaves its substrates at non-basic residues in the Golgi. PCSK9 clea...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Seidah, Nabil G., Sadr, Mohamad S., Chrétien, Michel, Mbikay, Majambu
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724608/
https://ncbi.nlm.nih.gov/pubmed/23775089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R113.481549
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