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The Proprotein Convertase PC7: UNIQUE ZYMOGEN ACTIVATION AND TRAFFICKING PATHWAYS

The zymogen activation mechanism and physiological functions of the most ancient and highly conserved basic amino acid-specific proprotein convertase 7 (PC7) are not known. Herein, we characterized the biosynthesis, subcellular localization, and trafficking of the membrane-bound full-length rat and...

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Detalhes bibliográficos
Main Authors: Rousselet, Estelle, Benjannet, Suzanne, Hamelin, Josée, Canuel, Maryssa, Seidah, Nabil G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3024769/
https://ncbi.nlm.nih.gov/pubmed/21075846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.192344
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