The secretory proprotein convertases furin, PC5, and PC7 activate VEGF-C to induce tumorigenesis

The secretory factor VEGF-C has been directly implicated in various physiological processes during embryogenesis and human cancers. However, the importance of the conversion of its precursor proVEGF-C to mature VEGF-C in tumorigenesis, and vessel formation and the identity of the protease(s) that re...

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Vydáno v:	J Clin Invest
Hlavní autoři:	Siegfried, Geraldine, Basak, Ajoy, Cromlish, James A., Benjannet, Suzanne, Marcinkiewicz, Jadwiga, Chrétien, Michel, Seidah, Nabil G., Khatib, Abdel-Majid
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Clinical Investigation 2003
Témata:	Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC156106/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12782675/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI17220
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