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The secretory proprotein convertases furin, PC5, and PC7 activate VEGF-C to induce tumorigenesis
The secretory factor VEGF-C has been directly implicated in various physiological processes during embryogenesis and human cancers. However, the importance of the conversion of its precursor proVEGF-C to mature VEGF-C in tumorigenesis, and vessel formation and the identity of the protease(s) that re...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC156106/ https://ncbi.nlm.nih.gov/pubmed/12782675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200317220 |
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