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In vivo functions of the proprotein convertase PC5/6 during mouse development: Gdf11 is a likely substrate
The proprotein convertase PC5/6 cleaves protein precursors after basic amino acids and is essential for implantation in CD1/129/Sv/C57BL/6 mixed-background mice. Conditional inactivation of Pcsk5 in the epiblast but not in the extraembryonic tissue bypassed early embryonic lethality but resulted in...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2299217/ https://ncbi.nlm.nih.gov/pubmed/18378898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0709428105 |
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