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In vivo functions of the proprotein convertase PC5/6 during mouse development: Gdf11 is a likely substrate

The proprotein convertase PC5/6 cleaves protein precursors after basic amino acids and is essential for implantation in CD1/129/Sv/C57BL/6 mixed-background mice. Conditional inactivation of Pcsk5 in the epiblast but not in the extraembryonic tissue bypassed early embryonic lethality but resulted in...

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Библиографические подробности
Главные авторы: Essalmani, Rachid, Zaid, Ahmed, Marcinkiewicz, Jadwiga, Chamberland, Ann, Pasquato, Antonella, Seidah, Nabil G., Prat, Annik
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2299217/
https://ncbi.nlm.nih.gov/pubmed/18378898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0709428105
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