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The proprotein convertase PC5/6 is protective against intestinal tumorigenesis: in vivo mouse model

BACKGROUND: The secretory basic amino acid-specific proprotein convertases (PCs) have often been associated with cancer/metastasis. By controlling the cleavage of cancer-associated proteins, PCs play key roles in multiple steps of cancer development. Most analyses of the implication of PCs in cancer...

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Autors principals: Sun, Xiaowei, Essalmani, Rachid, Seidah, Nabil G, Prat, Annik
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746178/
https://ncbi.nlm.nih.gov/pubmed/19737405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-8-73
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