Intravenous siRNA silencing of survivin enhances activity of mitomycin C in human bladder RT4 xenografts

PURPOSE: Survivin inhibits apoptosis and enables tumor cells to escape from therapy-induced senescence. High expression of survivin is associated with bladder cancer aggressiveness and recurrence. The present study evaluated if survivin expression is reduced by siRNA and if survivin silencing enhanc...

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Detaylı Bibliyografya
Yayımlandı:J Urol
Asıl Yazarlar: Cui, Minjian, Au, Jessie L.-S., Wientjes, M. Guillaume, O’Donnell, Michael A., Loughlin, Kevin R., Lu, Ze
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4512300/
https://ncbi.nlm.nih.gov/pubmed/25681288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.juro.2015.02.036
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