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Intravenous siRNA silencing of survivin enhances activity of mitomycin C in human bladder RT4 xenografts
PURPOSE: Survivin inhibits apoptosis and enables tumor cells to escape from therapy-induced senescence. High expression of survivin is associated with bladder cancer aggressiveness and recurrence. The present study evaluated if survivin expression is reduced by siRNA and if survivin silencing enhanc...
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| Publicado no: | J Urol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4512300/ https://ncbi.nlm.nih.gov/pubmed/25681288 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.juro.2015.02.036 |
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