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Targeting the heparin-binding domain of fibroblast growth factor receptor 1 as a potential cancer therapy
BACKGROUND: Aberrant activation of fibroblast growth factor receptors (FGFRs) deregulates cell proliferation and promotes cell survival, and may predispose to tumorigenesis. Therefore, selective inactivation of FGFRs is an important strategy for cancer therapy. Here as a proof-of-concept study, we d...
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| Опубликовано в: : | Mol Cancer |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4511971/ https://ncbi.nlm.nih.gov/pubmed/26201468 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0391-4 |
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