Heparan Sulfate Proteoglycans: Key Mediators of Stem Cell Function

door Ravikumar, Maanasa, Smith, Raymond Alexander Alfred, Nurcombe, Victor, Cool, Simon M.
Gepubliceerd in Front Cell Dev Biol (2020)

Age-Related Changes in the Inflammatory Status of Human Mesenchymal Stem Cells: Implications for Cell Therapy

door Zhang, Ying, Ravikumar, Maanasa, Ling, Ling, Nurcombe, Victor, Cool, Simon M.
Gepubliceerd in Stem Cell Reports (2021)

Glycosaminoglycans modulate RANKL induced osteoclastogenesis

door Ling, Ling, Murali, Sadasivam, Stein, Gary S., van Wijnen, Andre J., Cool, Simon M.
Gepubliceerd in 2010

Comparative Assessment of the Effects of Gender-specific Heparan Sulfates on Mesenchymal Stem Cells

door Murali, Sadasivam, Leong, Denise F. M., Lee, Jaslyn J. L., Cool, Simon M., Nurcombe, Victor
Gepubliceerd in 2011

Complexation and Sequestration of BMP-2 from an ECM Mimetic Hyaluronan Gel for Improved Bone Formation

door Kisiel, Marta, Klar, Agnieszka S., Ventura, Manuela, Buijs, Jos, Mafina, Marc-Krystelle, Cool, Simon M., Hilborn, Jöns
Gepubliceerd in 2013

A Versatile Protocol for Studying Calvarial Bone Defect Healing in a Mouse Model

door Samsonraj, Rebekah M., Dudakovic, Amel, Zan, Pengfei, Pichurin, Oksana, Cool, Simon M., van Wijnen, Andre J.
Gepubliceerd in Tissue Eng Part C Methods (2017)

Concise Review: Multifaceted Characterization of Human Mesenchymal Stem Cells for Use in Regenerative Medicine

door Samsonraj, Rebekah M., Raghunath, Michael, Nurcombe, Victor, Hui, James H., van Wijnen, Andre J., Cool, Simon M.
Gepubliceerd in Stem Cells Transl Med (2017)

Improved recovery from limb ischaemia by delivery of an affinity-isolated heparan sulphate

door Poon, Selina, Lu, Xiaohua, Smith, Raymond A. A., Ho, Pei, Bhakoo, Kishore, Nurcombe, Victor, Cool, Simon M.
Gepubliceerd in Angiogenesis (2018)

Fibroblast growth factor receptor 1 is principally responsible for fibroblast growth factor 2-induced catabolic activities in human articular chondrocytes

door Yan, Dongyao, Chen, Di, Cool, Simon M, van Wijnen, Andre J, Mikecz, Katalin, Murphy, Gillian, Im, Hee-Jeong
Gepubliceerd in 2011

Heparan sulfate proteoglycans and human breast cancer epithelial cell tumorigenicity

door Okolicsanyi, Rachel K., van Wijnen, Andre J., Cool, Simon M., Stein, Gary S., Griffiths, Lyn R., Haupt, Larisa M.
Gepubliceerd in J Cell Biochem (2014)

Targeting the heparin-binding domain of fibroblast growth factor receptor 1 as a potential cancer therapy

door Ling, Ling, Tan, Si Kee, Goh, Ting Hwee, Cheung, Edwin, Nurcombe, Victor, van Wijnen, Andre J., Cool, Simon M.
Gepubliceerd in Mol Cancer (2015)

Growth Differentiation Factor 5-Mediated Enhancement of Chondrocyte Phenotype Is Inhibited by Heparin: Implications for the Use of Heparin in the Clinic and in Tissue Engineering A...

door Ayerst, Bethanie I., Smith, Raymond A.A., Nurcombe, Victor, Day, Anthony J., Merry, Catherine L.R., Cool, Simon M.
Gepubliceerd in Tissue Eng Part A (2017)

Microfluidic Screening Reveals Heparan Sulfate Enhances Human Mesenchymal Stem Cell Growth by Modulating Fibroblast Growth Factor‐2 Transport

door Titmarsh, Drew M., Tan, Clarissa L.L., Glass, Nick R., Nurcombe, Victor, Cooper‐White, Justin J., Cool, Simon M.
Gepubliceerd in Stem Cells Transl Med (2017)

Synergism between Wnt3a and Heparin Enhances Osteogenesis via a Phosphoinositide 3-Kinase/Akt/RUNX2 Pathway

door Ling, Ling, Dombrowski, Christian, Foong, Kin Mun, Haupt, Larisa M., Stein, Gary S., Nurcombe, Victor, van Wijnen, Andre J., Cool, Simon M.
Gepubliceerd in 2010

Osteogenic Stimulation of Human Adipose‐Derived Mesenchymal Stem Cells Using a Fungal Metabolite That Suppresses the Polycomb Group Protein EZH2

door Samsonraj, Rebekah M., Dudakovic, Amel, Manzar, Bushra, Sen, Buer, Dietz, Allan B., Cool, Simon M., Rubin, Janet, van Wijnen, Andre J.
Gepubliceerd in Stem Cells Transl Med (2017)

Human Mesenchymal Stem Cells Retain Multilineage Differentiation Capacity Including Neural Marker Expression after Extended In Vitro Expansion

door Okolicsanyi, Rachel K., Camilleri, Emily T., Oikari, Lotta E, Yu, Chieh, Cool, Simon M., van Wijnen, Andre J., Griffiths, Lyn R., Haupt, Larisa M.
Gepubliceerd in PLoS One (2015)

Bone Marrow-Derived Heparan Sulfate Potentiates The Osteogenic Activity Of Bone Morphogenetic Protein-2 (BMP-2)

door Bramono, Diah S., Murali, Sadasivam, Rai, Bina, Ling, Ling, Poh, Wei Theng, Lim, Zophia Xuehui, Stein, Gary S., Nurcombe, Victor, van Wijnen, Andre J., Cool, Simon M.
Gepubliceerd in 2011

Hyaluronic acid-based hydrogels functionalized with heparin that support controlled release of bioactive BMP-2

door Bhakta, Gajadhar, Rai, Bina, Lim, Zophia X.H., Hui, James H., Stein, Gary S., van Wijnen, Andre J., Nurcombe, Victor, Prestwich, Glenn D., Cool, Simon M.
Gepubliceerd in 2012

Establishing Criteria for Human Mesenchymal Stem Cell Potency

door Samsonraj, Rebekah M., Rai, Bina, Sathiyanathan, Padmapriya, Puan, Kia Joo, Rötzschke, Olaf, Hui, James H., Raghunath, Michael, Stanton, Lawrence W., Nurcombe, Victor, Cool, Simon M.
Gepubliceerd in Stem Cells (2015)

Fibrin glue mediated delivery of bone anabolic reagents to enhance healing of tendon to bone

door Soreide, Endre, Denbeigh, Janet M., Lewallen, Eric A., Samsonraj, Rebekah M., Berglund, Lawrence J., Dudakovic, Amel, Cool, Simon M., Nordsletten, Lars, Kakar, Sanjeev, van Wijnen, Andre J.
Gepubliceerd in J Cell Biochem (2018)