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Targeting the heparin-binding domain of fibroblast growth factor receptor 1 as a potential cancer therapy
BACKGROUND: Aberrant activation of fibroblast growth factor receptors (FGFRs) deregulates cell proliferation and promotes cell survival, and may predispose to tumorigenesis. Therefore, selective inactivation of FGFRs is an important strategy for cancer therapy. Here as a proof-of-concept study, we d...
में बचाया:
| में प्रकाशित: | Mol Cancer |
|---|---|
| मुख्य लेखकों: | , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
BioMed Central
2015
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4511971/ https://ncbi.nlm.nih.gov/pubmed/26201468 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0391-4 |
| टैग : |
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