Tetanus toxoid and CCL3 improve DC vaccines in mice and glioblastoma patients

Upon stimulation, dendritic cells (DCs) mature and migrate to draining lymph nodes to induce immune responses(1). As such, autologous DCs generated ex vivo have been pulsed with tumor antigens and injected back into patients as immunotherapy. While DC vaccines have shown limited promise in the treat...

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Publicat a:Nature
Autors principals: Mitchell, Duane A., Batich, Kristen A., Gunn, Michael D., Huang, Min-Nung, Sanchez-Perez, Luis, Nair, Smita K., Congdon, Kendra L., Reap, Elizabeth A., Archer, Gary E., Desjardins, Annick, Friedman, Allan H., Friedman, Henry S., Herndon, James E., Coan, April, McLendon, Roger E., Reardon, David A., Vredenburgh, James J., Bigner, Darell D., Sampson, John H.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4510871/
https://ncbi.nlm.nih.gov/pubmed/25762141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14320
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