Phase II study of carboplatin, irinotecan and bevacizumab for recurrent glioblastoma after progression on bevacizumab therapy

BACKGROUND: We evaluated the efficacy of carboplatin, irinotecan and bevacizumab among recurrent glioblastoma (GBM) patients after prior progression on bevacizumab therapy in a phase 2, open-label, single-arm trial. METHODS: Eligible patients received carboplatin (area under the plasma curve [AUC] 4...

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Bibliografiske detaljer
Main Authors: Reardon, David A., Desjardins, Annick, Peters, Katherine B., Vredenburgh, James J., Gururangan, Sridharan, Sampson, John H., McLendon, Roger E., Herndon, James E., Coan, April, Threatt, Stevie, Friedman, Allan H., Friedman, Henry S.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158844/
https://ncbi.nlm.nih.gov/pubmed/21590689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.26188
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