Phase II study of metronomic chemotherapy with bevacizumab for recurrent glioblastoma after progression on bevacizumab therapy

We evaluated the efficacy of metronomic etoposide or temozolomide administered with bevacizumab among recurrent glioblastoma (GBM) patients who progressed on prior bevacizumab therapy in a phase 2, open-label, two-arm trial. Twenty-three patients received bevacizumab (10 mg/kg) every 2 weeks with ei...

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Hauptverfasser: Reardon, David A., Desjardins, Annick, Peters, Katherine, Gururangan, Sridharan, Sampson, John, Rich, Jeremy N., McLendon, Roger, Herndon, James E., Marcello, Jennifer, Threatt, Stevie, Friedman, Allan H., Vredenburgh, James J., Friedman, Henry S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3102515/
https://ncbi.nlm.nih.gov/pubmed/20853132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-010-0403-6
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