Tetanus toxoid and CCL3 improve DC vaccines in mice and glioblastoma patients

Upon stimulation, dendritic cells (DCs) mature and migrate to draining lymph nodes to induce immune responses(1). As such, autologous DCs generated ex vivo have been pulsed with tumor antigens and injected back into patients as immunotherapy. While DC vaccines have shown limited promise in the treat...

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Détails bibliographiques
Publié dans:Nature
Auteurs principaux: Mitchell, Duane A., Batich, Kristen A., Gunn, Michael D., Huang, Min-Nung, Sanchez-Perez, Luis, Nair, Smita K., Congdon, Kendra L., Reap, Elizabeth A., Archer, Gary E., Desjardins, Annick, Friedman, Allan H., Friedman, Henry S., Herndon, James E., Coan, April, McLendon, Roger E., Reardon, David A., Vredenburgh, James J., Bigner, Darell D., Sampson, John H.
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4510871/
https://ncbi.nlm.nih.gov/pubmed/25762141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14320
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