Inhibition of soluble epoxide hydrolase increases coronary perfusion in mice

Roles of soluble epoxide hydrolase (sEH), the enzyme responsible for hydrolysis of epoxyeicosatrienoic acids (EETs) to their diols (DHETs), in the coronary circulation and cardiac function remain unknown. We tested the hypothesis that compromising EET hydrolysis/degradation, via sEH deficiency, lowe...

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書目詳細資料
發表在:Physiol Rep
Main Authors: Qin, Jun, Sun, Dong, Jiang, Houli, Kandhi, Sharath, Froogh, Ghezal, Hwang, Sung Hee, Hammock, Bruce D, Wolin, Michael S, Thompson, Carl I, Hintze, Thomas H, Huang, An
格式: Artigo
語言:Inglês
出版: John Wiley & Sons, Ltd 2015
主題:
Original Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4510629/
https://ncbi.nlm.nih.gov/pubmed/26071213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12427
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