EET-dependent potentiation of pulmonary arterial pressure: sex-different regulation of soluble epoxide hydrolase

We tested the hypothesis that suppression of epoxyeicosatrienoic acid (EET) metabolism via genetic knockout of the gene for soluble epoxide hydrolase (sEH-KO), or female-specific downregulation of sEH expression, plays a role in the potentiation of pulmonary hypertension. We used male (M) and female...

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Vydáno v:Am J Physiol Lung Cell Mol Physiol
Hlavní autoři: Kandhi, Sharath, Qin, Jun, Froogh, Ghezal, Jiang, Houli, Luo, Meng, Wolin, Michael S., Huang, An, Sun, Dong
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4683314/
https://ncbi.nlm.nih.gov/pubmed/26498250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00208.2015
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