EETs promote hypoxic pulmonary vasoconstriction via constrictor prostanoids

To test the hypothesis that epoxyeicosatrienoic acids (EETs) facilitate pulmonary responses to hypoxia, male wild-type (WT) and soluble-epoxide hydrolase knockout (sEH-KO) mice, and WT mice chronically fed a sEH inhibitor (t-TUCB; 1 mg·kg(−1)·day(−1)) were used. Right ventricular systolic pressure (...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Kandhi, Sharath, Zhang, Bin, Froogh, Ghezal, Qin, Jun, Alruwaili, Norah, Le, Yicong, Yang, Yang-Ming, Hwang, Sung Hee, Hammock, Bruce D., Wolin, Michael S., Huang, An, Sun, Dong
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582931/
https://ncbi.nlm.nih.gov/pubmed/28450284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00038.2017
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