Inhibition of soluble epoxide hydrolase increases coronary perfusion in mice

Roles of soluble epoxide hydrolase (sEH), the enzyme responsible for hydrolysis of epoxyeicosatrienoic acids (EETs) to their diols (DHETs), in the coronary circulation and cardiac function remain unknown. We tested the hypothesis that compromising EET hydrolysis/degradation, via sEH deficiency, lowe...

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Detalhes bibliográficos
Publicado no:Physiol Rep
Main Authors: Qin, Jun, Sun, Dong, Jiang, Houli, Kandhi, Sharath, Froogh, Ghezal, Hwang, Sung Hee, Hammock, Bruce D, Wolin, Michael S, Thompson, Carl I, Hintze, Thomas H, Huang, An
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4510629/
https://ncbi.nlm.nih.gov/pubmed/26071213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12427
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