Inhibition of soluble epoxide hydrolase increases coronary perfusion in mice

Roles of soluble epoxide hydrolase (sEH), the enzyme responsible for hydrolysis of epoxyeicosatrienoic acids (EETs) to their diols (DHETs), in the coronary circulation and cardiac function remain unknown. We tested the hypothesis that compromising EET hydrolysis/degradation, via sEH deficiency, lowe...

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Dades bibliogràfiques
Publicat a:Physiol Rep
Autors principals: Qin, Jun, Sun, Dong, Jiang, Houli, Kandhi, Sharath, Froogh, Ghezal, Hwang, Sung Hee, Hammock, Bruce D, Wolin, Michael S, Thompson, Carl I, Hintze, Thomas H, Huang, An
Format: Artigo
Idioma:Inglês
Publicat: John Wiley & Sons, Ltd 2015
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4510629/
https://ncbi.nlm.nih.gov/pubmed/26071213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12427
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