טוען...

XPO1/CRM1 Inhibition Causes Antitumor Effects by Mitochondrial Accumulation of eIF5A

PURPOSE: XPO1 inhibitors have shown promise for cancer treatment and yet the underlying mechanisms for the antitumor effects are not well understood. In this study, we explored the usefulness of selective inhibitors of nuclear export (SINE) compounds that are specific inhibitors of XPO1. EXPERIMENTA...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Clin Cancer Res
Main Authors: Miyake, Takahito, Pradeep, Sunila, Wu, Sherry Y., Rupaimoole, Rajesha, Zand, Behrouz, Wen, Yunfei, Gharpure, Kshipra M., Nagaraja, Archana S., Hu, Wei, Cho, Min Soon, Dalton, Heather J., Previs, Rebecca A., Taylor, Morgan L., Hisamatsu, Takeshi, Kang, Yu, Liu, Tao, Shacham, Sharon, McCauley, Dilara, Hawke, David H., Wiktorowicz, John E., Coleman, Robert L., Sood, Anil K.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2015
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506247/
https://ncbi.nlm.nih.gov/pubmed/25878333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-1953
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!