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Azole Antifungal Agents To Treat the Human Pathogens Acanthamoeba castellanii and Acanthamoeba polyphaga through Inhibition of Sterol 14α-Demethylase (CYP51)

In this study, we investigate the amebicidal activities of the pharmaceutical triazole CYP51 inhibitors fluconazole, itraconazole, and voriconazole against Acanthamoeba castellanii and Acanthamoeba polyphaga and assess their potential as therapeutic agents against Acanthamoeba infections in humans....

詳細記述

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Lamb, David C., Warrilow, Andrew G. S., Rolley, Nicola J., Parker, Josie E., Nes, W. David, Smith, Stephen N., Kelly, Diane E., Kelly, Steven L.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505289/
https://ncbi.nlm.nih.gov/pubmed/26014948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00476-15
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