Heavy Metal Ion Regulation of Gene Expression: MECHANISMS BY WHICH LEAD INHIBITS OSTEOBLASTIC BONE-FORMING ACTIVITY THROUGH MODULATION OF THE Wnt/β-CATENIN SIGNALING PATHWAY

Exposure to lead (Pb) from environmental sources remains an overlooked and serious public health risk. Starting in childhood, Pb in the skeleton can disrupt epiphyseal plate function, constrain the growth of long bones, and prevent attainment of a high peak bone mass, all of which will increase susc...

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Bibliografiset tiedot
Julkaisussa:J Biol Chem
Päätekijät: Beier, Eric E., Sheu, Tzong-jen, Dang, Deborah, Holz, Jonathan D., Ubayawardena, Resika, Babij, Philip, Puzas, J. Edward
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2015
Aiheet:
Molecular Bases of Disease
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505064/
https://ncbi.nlm.nih.gov/pubmed/25975268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.629204
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