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Lead Induces an Osteoarthritis-like Phenotype in Articular Chondrocytes through Disruption of TGF-β Signaling
Lead remains a significant environmental toxin, and we believe we may have identified a novel target of lead toxicity in articular chondrocytes. These cells are responsible for the maintenance of joint matrix, and do so under the regulation of TGF-β signaling. As lead is concentrated in articular ca...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3839422/ https://ncbi.nlm.nih.gov/pubmed/22517267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.22117 |
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