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Elevated Lifetime Lead Exposure Impedes Osteoclast Activity and Produces an Increase in Bone Mass in Adolescent Mice

The heavy metal lead (Pb) has a deleterious effect on skeletal health. Because bone mass is maintained through a balance of bone formation and resorption, it is important to understand the effect of Pb levels on osteoblastic and osteoclastic activity. Pb exposure is associated with low bone mass in...

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Publicat a:Toxicol Sci
Autors principals: Beier, Eric E., Holz, Jonathan D., Sheu, Tzong-Jen, Puzas, J. Edward
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4900215/
https://ncbi.nlm.nih.gov/pubmed/26518054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfv234
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