Inhibition of beta-catenin signaling by Pb leads to incomplete fracture healing

There is strong evidence in the clinical literature to suggest that elevated lead (Pb) exposure impairs fracture healing. Since Pb has been demonstrated to inhibit bone formation, and Wnt signaling is an important anabolic pathway in chondrocyte maturation and endochondral ossification, we investiga...

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Bibliografske podrobnosti
izdano v:J Orthop Res
Main Authors: Beier, Eric E, Buckley, Taylor, Yukata, Kiminori, Sheu, Tzong-Jen, O’Keefe, Regis, Zuscik, Michael J, Puzas, J Edward
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314692/
https://ncbi.nlm.nih.gov/pubmed/25044211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.22677
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