A carregar...
The pseudokinase domain of JAK2 is a dual-specificity protein kinase that negatively regulates cytokine signaling
Human JAK2 tyrosine kinase mediates signaling through numerous cytokine receptors. The JAK2 JH2 domain functions as a negative regulator and is presumed to be a catalytically inactive pseudokinase, but the mechanism(s) for its inhibition of JAK2 remains unknown. Mutations in JH2 lead to increased JA...
Na minha lista:
| Publicado no: | Nat Struct Mol Biol |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4504201/ https://ncbi.nlm.nih.gov/pubmed/21841788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2099 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|