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Atom-by-atom engineering of voltage-gated ion channels: Magnified insights into function and pharmacology
Unnatural amino acid incorporation into ion channels has proven to be a valuable approach to interrogate detailed hypotheses arising from atomic resolution structures. In this short review, we provide a brief overview of some of the basic principles and methods for incorporation of unnatural amino a...
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| Veröffentlicht in: | J Physiol |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley & Sons, Ltd
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4500348/ https://ncbi.nlm.nih.gov/pubmed/25640301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2014.287714 |
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