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Voltage-Dependent Gating in a “Voltage Sensor-Less” Ion Channel

The voltage sensitivity of voltage-gated cation channels is primarily attributed to conformational changes of a four transmembrane segment voltage-sensing domain, conserved across many levels of biological complexity. We have identified a remarkable point mutation that confers significant voltage de...

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Detalles Bibliográficos
Main Authors: Kurata, Harley T., Rapedius, Markus, Kleinman, Marc J., Baukrowitz, Thomas ., Nichols, Colin G.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826373/
https://ncbi.nlm.nih.gov/pubmed/20208975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000315
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