BEND3 represses rDNA transcription by stabilizing a NoRC component via USP21 deubiquitinase

Ribosome biogenesis dictates the translational capacity of cells. Several mechanisms establish and maintain transcriptional output from eukaryotic ribosomal DNA (rDNA) loci. rDNA silencing is one such mechanism that ensures the inactivity and hence the maintenance of a silenced state of a subset of...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Khan, Abid, Giri, Sumanprava, Wang, Yating, Chakraborty, Arindam, Ghosh, Archit K., Anantharaman, Aparna, Aggarwal, Vasudha, Sathyan, Kizhakke M., Ha, Taekjip, Prasanth, Kannanganattu V., Prasanth, Supriya G.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2015
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4500215/
https://ncbi.nlm.nih.gov/pubmed/26100909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1424705112
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