BEND3 represses rDNA transcription by stabilizing a NoRC component via USP21 deubiquitinase

Ribosome biogenesis dictates the translational capacity of cells. Several mechanisms establish and maintain transcriptional output from eukaryotic ribosomal DNA (rDNA) loci. rDNA silencing is one such mechanism that ensures the inactivity and hence the maintenance of a silenced state of a subset of...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Khan, Abid, Giri, Sumanprava, Wang, Yating, Chakraborty, Arindam, Ghosh, Archit K., Anantharaman, Aparna, Aggarwal, Vasudha, Sathyan, Kizhakke M., Ha, Taekjip, Prasanth, Kannanganattu V., Prasanth, Supriya G.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2015
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4500215/
https://ncbi.nlm.nih.gov/pubmed/26100909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1424705112
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