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The structure of NoRC-associated RNA is crucial for targeting the chromatin remodelling complex NoRC to the nucleolus

Silencing of ribosomal RNA genes (rDNA) requires binding of the chromatin remodelling complex NoRC to RNA that is complementary to the rDNA promoter. NoRC-associated RNA (pRNA) folds into a conserved stem–loop structure that is required for nucleolar localization and rDNA silencing. Mutations that d...

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Bibliografische gegevens
Hoofdauteurs: Mayer, Christine, Neubert, Melanie, Grummt, Ingrid
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2008
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2515205/
https://ncbi.nlm.nih.gov/pubmed/18600236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2008.109
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