The structure of NoRC-associated RNA is crucial for targeting the chromatin remodelling complex NoRC to the nucleolus

Silencing of ribosomal RNA genes (rDNA) requires binding of the chromatin remodelling complex NoRC to RNA that is complementary to the rDNA promoter. NoRC-associated RNA (pRNA) folds into a conserved stem–loop structure that is required for nucleolar localization and rDNA silencing. Mutations that d...

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Hlavní autoři: Mayer, Christine, Neubert, Melanie, Grummt, Ingrid
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2008
Témata:
Scientific Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2515205/
https://ncbi.nlm.nih.gov/pubmed/18600236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2008.109
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