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The chromatin remodeling complex NoRC targets HDAC1 to the ribosomal gene promoter and represses RNA polymerase I transcription

Mammalian chromatin remodeling complexes are involved in both activation and repression of transcription. Here, we show that NoRC, a SNF2h- containing nucleolar chromatin remodeling complex, represses ribosomal gene transcription. NoRC-mediated rDNA silencing was alleviated by trichostatin A, indica...

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Autors principals: Zhou, Yonggang, Santoro, Raffaella, Grummt, Ingrid
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC126197/
https://ncbi.nlm.nih.gov/pubmed/12198165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf460
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