BEND3 represses rDNA transcription by stabilizing a NoRC component via USP21 deubiquitinase

Ribosome biogenesis dictates the translational capacity of cells. Several mechanisms establish and maintain transcriptional output from eukaryotic ribosomal DNA (rDNA) loci. rDNA silencing is one such mechanism that ensures the inactivity and hence the maintenance of a silenced state of a subset of...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Khan, Abid, Giri, Sumanprava, Wang, Yating, Chakraborty, Arindam, Ghosh, Archit K., Anantharaman, Aparna, Aggarwal, Vasudha, Sathyan, Kizhakke M., Ha, Taekjip, Prasanth, Kannanganattu V., Prasanth, Supriya G.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2015
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4500215/
https://ncbi.nlm.nih.gov/pubmed/26100909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1424705112
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