Modulation of LSD1 phosphorylation by CK2/WIP1 regulates RNF168-dependent 53BP1 recruitment in response to DNA damage

Proper DNA damage response is essential for the maintenance of genome integrity. The E3 ligase RNF168 deficiency fully prevents both the initial recruitment and retention of 53BP1 at sites of DNA damage. In response to DNA damage, RNF168-dependent recruitment of the lysine-specific demethylase LSD1...

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Detaylı Bibliyografya
Yayımlandı:Nucleic Acids Res
Asıl Yazarlar: Peng, Bin, Wang, Jing, Hu, Yuan, Zhao, Hongli, Hou, Wenya, Zhao, Hongchang, Wang, Hailong, Liao, Ji, Xu, Xingzhi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2015
Konular:
Genome Integrity, Repair and Replication
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4499147/
https://ncbi.nlm.nih.gov/pubmed/25999347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv528
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