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Structural Basis for Avoidance of Promutagenic DNA Repair by MutY Adenine DNA Glycosylase

The highly mutagenic A:oxoG (8-oxoguanine) base pair in DNA most frequently arises by aberrant replication of the primary oxidative lesion C:oxoG. This lesion is particularly insidious because neither of its constituent nucleobases faithfully transmit genetic information from the original C:G base p...

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Vydáno v:J Biol Chem
Hlavní autoři: Wang, Lan, Lee, Seung-Joo, Verdine, Gregory L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4498048/
https://ncbi.nlm.nih.gov/pubmed/25995449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.657866
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