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Structural basis for finding OG lesions and avoiding undamaged G by the DNA glycosylase MutY
The adenine glycosylase MutY selectively initiates repair of OG:A lesions and, by comparison, avoids G:A mispairs. The ability to distinguish these closely related substrates relies on the C-terminal domain of MutY which structurally resembles MutT. To understand the mechanism for substrate specific...
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| Vydáno v: | ACS Chem Biol |
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| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7069122/ https://ncbi.nlm.nih.gov/pubmed/31829624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.9b00639 |
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