Загрузка...
Unnatural substrates reveal the importance of 8-oxoguanine for in vivo mismatch repair by MutY
Escherchia coli MutY plays an important role in preventing mutations associated with the oxidative lesion 7,8-dihydro-8-oxo-2′-deoxyguanosine (OG) in DNA by excising adenines from OG:A mismatches as the first step of base excision repair. To determine the importance of specific steps in the base pai...
Сохранить в:
| Главные авторы: | , , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2007
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2759348/ https://ncbi.nlm.nih.gov/pubmed/18026095 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2007.40 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|